منابع مشابه
Genomic Discoveries and Personalized Medicine in Neurological Diseases.
In the past decades, we have witnessed dramatic changes in clinical diagnoses and treatments due to the revolutions of genomics and personalized medicine. Undoubtedly we also met many challenges when we use those advanced technologies in drug discovery and development. In this review, we describe when genomic information is applied in personal healthcare in general. We illustrate some case exam...
متن کامل[Role of genomic medicine in middle and inner ear diseases].
INTRODUCTION AND OBJECTIVES Genomic medicine investigates groups of genetic markers that determine susceptibility for complex diseases. The aim of this review was to introduce genomics to the clinical otorhinolaryngologist. Technological advances in genotyping and sequencing that have facilitated genome-wide association studies in common causes of hearing loss during the last years are summaris...
متن کاملAsbestos-related Lung Diseases: A Brief Update
Health risks from asbestos exposures have been evaluated, considering past professional histories when exposures at workplaces were higher than today. A linear no-threshold (LNT) model has been applied, although its relevance is unproven. Fibers are often found in the lungs and pleura of deceased people. Fiber findings do not prove that a disease is caused by asbestos. It is reasonable to assum...
متن کاملHuman Genetics and Genomic Medicine
Gholson Lyon with Max Doerfel, Jason O’Rawe, Yiyang Wu, Prashant Kota The Lyon laboratory focuses on analyzing human genetic variation and its role in severe idiopathic neuropsychiatric disorders. We do this by studying large pedigrees living in the same geographic location, where one can study the expressivity and segregation of variants in a similar environmental background and with fewer pop...
متن کاملGenomic medicine and atrial fibrillation.
Recent developments and improved understanding in genomics (the interactions and functions of genes) have profoundly changed the perspective of researchers and medical practitioners toward diseases that had previously been associated with environmental factors alone (1). It is now widely recognized that many common disorders, such as heart disease, cancer, infections, Parkinson’s disease, and A...
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ژورنال
عنوان ژورنال: American Journal of Respiratory and Critical Care Medicine
سال: 2012
ISSN: 1073-449X,1535-4970
DOI: 10.1164/rccm.201203-0569ws